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Medication management

At some point in everyone’s diabetes journey, medications are used to help keep blood sugar in a target range. Treatment plans can change depending on the person and the progression of their diabetes. Diabetes changes over time. Your medicines may need to change too. You may also need medications to protect your heart, kidneys, liver and other organs for long-term health.

Not all diabetes treatments work for everyone. Don’t feel bad if you find you need to make changes or stop certain medications. Your health-care team can help you find the medications that work best for you.

Why do you need medications to manage diabetes?

A person writing on a piece of paper
  1. Medications are used to help keep blood sugar levels in a healthy target range when the body can no longer do this on its own.
  2. Medications are used to help protect other organs such as the heart, kidneys, liver and help prevent complications.
  3. Medications help manage other health conditions such as high blood pressure and high cholesterol.

Where and how medications work


Medication helps:
  • cells use insulin better
  • the pancreas make more insulin
  • the pancreas make less glucagon, a hormone which lowers the amount of sugar released from the liver into the blood
  • the intestines to decrease sugar absorption and allow more to leave the body
  • the muscles use more sugar which means less in the blood
  • the brain to feel more satisfied with less food
  • the kidneys to increase the amount of sugar filtered and removed from the body

Types of medications

Medication Function
Biguanides
  • help your body use its own insulin better (improves insulin sensitivity)
  • lower the amount of sugar released from the liver into the bloodstream
SGLT2 Inhibitors
  • decrease blood sugar by removing more sugar through the kidneys when you go to the bathroom
GLP-1 Inhibitor Agonists
  • increase insulin release from the pancreas
  • decrease glucagon release from the pancreas so the liver does not release more sugar
  • slow stomach emptying so you feel full sooner and stay full longer
GIP/GLP-1 Inhibitor Agonists
  • increase insulin release from the pancreas
  • decrease glucagon release from the pancreas
  • slow stomach emptying
DPP-4 Inhibitors
  • help the pancreas release more insulin and reduce glucagon release
Insulin Secretagogues
  • help the pancreas release more insulin
Alpha-glucosidase Inhibitors
  • slow the digestion and absorption of carbohydrates in the intestines
Thiazolidinediones
  • help your body use insulin better (improves insulin sensitivity)
  • decrease glucose released from the liver
Insulin
  • everyone with type 1 diabetes uses insulin to keep blood sugar stable
  • many people with type 2 diabetes also use insulin
  • helps manage blood sugar
  • helps prevent both short-term and long-term health concerns related to living with diabetes
Other medications to help reduce or treat complications related to diabetes may also be prescribed. These could include medications to control or reduce heart, kidney or liver disease or help with nerves and circulation.

Tips for medication management

  • Take medication as directed by your pharmacist or doctor including timing before, during or after a meal. This helps manage blood sugar and prevent spikes and/or lows especially around mealtimes.
  • Eat meals and snacks at as close to the same time each day.
  • Depending on the medications you take you might be at risk for low blood sugar.  Carry fast acting sugar sources such as glucose tablets, small juice boxes or candy with you when you are away from home.
  • Side effects can happen, especially when just starting a medication. If the medication is not working for you speak to your health-care team.
  • If you miss a pill, take it as soon as you remember unless it is almost time to take your next regular dose, then skip the missed dose. Never double your dose to make up for a missed one.

 

Medication can be a critical part of diabetes care, however treatment plans can change depending on the person and the type of diabetes. Some people can manage diabetes with healthy eating, exercise and/or medication, while others may require insulin. 

Understanding diabetes medications and management

Get to know the basics of diabetes medication and monitoring your levels.

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